Paraguay Travel Health Guide for US Travelers

A physician-reviewed health and safety guide for Americans traveling to the Republic of Paraguay

CDC & WHO Aligned Asuncion, Paraguay US State Dept: Level 1 — Exercise Normal Precautions Medically Reviewed 2025
U.S. State Department Travel Advisory — Level 1
As of 2026, the U.S. advises Exercise Normal Precautions in Paraguay. Travel is generally manageable, with primary concerns including mosquito-borne illness, road safety, and petty crime in urban areas.
Paraguay travel health guide for US travelers
Paraguay flag Republic of Paraguay Capital: Asuncion  |  Region: South America  |  Languages: Spanish, Guarani

Before You Travel to Paraguay

Paraguay travel planning should include vaccine review, mosquito-borne illness prevention, and routine safety preparation. Schedule a pre-travel health appointment 4-8 weeks before departure.

Travel Health Consultation

Discuss hepatitis A/B, typhoid, and yellow fever requirements by route.

Insurance

Carry travel health insurance details and emergency assistance contacts.

Medical Kit

Pack regular prescriptions, ORS, antidiarrheal treatment, and mosquito repellent.

Documents & STEP

Enroll in STEP and keep document backups both online and offline.


Yellow Fever in Paraguay

Yellow fever considerations: Paraguay may require yellow fever proof based on itinerary and has regional risk context in South America. Review current CDC and entry guidance before travel.
Regional relevanceYellow fever guidance may apply by route
Certificate planningVerify entry rules ahead of departure
Clinic timingAllow adequate lead time if vaccination is needed

Malaria in Paraguay

Low/limited concern for most itineraries: Routine prophylaxis is not typically required for many standard trips, but always confirm by exact travel route.
Route-specific reviewAssess rural/border travel separately
Mosquito preventionImportant for dengue/chikungunya risk reduction
Fever protocolSeek care for persistent fever

Recommended Vaccines for Paraguay

RECOMMENDED

Hepatitis A, Hepatitis B, Typhoid

Common recommendations depending on itinerary and exposure.

SELECTED

Yellow Fever

May be recommended/required depending on itinerary and crossing points.

ROUTINE

MMR, Tdap, Polio, Flu, COVID-19

Ensure all routine vaccines are current.


Healthcare System in Paraguay

Private care in Asuncion generally offers better resources than many public facilities. Outside major cities, access to specialized care may be limited.

Asuncion Care Access

Higher concentration of private clinics and specialists.

Rural Care Limitations

Longer transfer times and lower resource availability are common.

Payment

Private facilities may request upfront payment or guarantees.


Emergency Numbers in Paraguay

141Emergency medical services
911Police emergency
132Fire
+595 21 213 715US Embassy Asuncion

Nature, Climate & Safety Risks

Heat & Humidity

High temperatures can drive dehydration and heat-related illness.

Mosquito-Borne Disease

Dengue risk exists; daytime bite prevention is important.

Road Safety

Night driving and long-distance routes increase traffic injury risk.


Crime & Personal Safety

Most visits are uneventful, but petty theft and opportunistic crime can occur in urban areas. Use standard city safety habits and secure valuables.

Petty Theft

Be cautious in crowded transit points and markets.

ATM/Cash Safety

Use trusted ATMs and avoid displaying large amounts of cash.

Transport Choices

Use reputable transport providers, especially after dark.


Pre-Departure Checklist for Paraguay

  • Confirm vaccine recommendations and yellow fever certificate requirements by route
  • Pack mosquito repellent and hydration essentials
  • Arrange travel insurance and emergency payment backup
  • Store digital copies of IDs and prescriptions
  • Register in STEP and save embassy contacts

Map

Top Things to Do

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Best Restaurants

Find top-rated places to eat.