Madagascar Travel Health Guide for US Travelers

A physician-reviewed health and safety guide for Americans traveling to the Republic of Madagascar

CDC & WHO Aligned Antananarivo, Madagascar US State Dept: Level 2 — Exercise Increased Caution Medically Reviewed 2025
Advisory Snapshot: Crime, road safety, and limited advanced healthcare are practical concerns. Check live advisories before departure.

Before You Travel

Travel Clinic Visit

Book 4-8 weeks before departure for vaccines and malaria planning.

Medical Insurance

Carry insurance with emergency evacuation coverage.

Medication Prep

Bring full trip supply in original packaging plus extras.


Yellow Fever & Malaria

Yellow fever: No local yellow fever transmission, but certificate rules can apply if arriving from a risk country.
Malaria: Risk exists in many regions. Chemoprophylaxis and strict mosquito-bite prevention are commonly advised.
Tip: Confirm risk by exact route and elevation, not just country name.

Vaccines Commonly Discussed

Hepatitis A, Typhoid, Hepatitis B

Frequently recommended for many travelers.

Rabies (selected travelers)

Consider for longer stays, remote areas, or animal exposure risk.

Routine Boosters

MMR, Tdap, polio, influenza, and COVID-19 should be current.


Healthcare Access

Higher-level care is concentrated in Antananarivo. Outside major cities, facilities and supplies can be limited.
Evacuation planning: Serious illness/injury may require air evacuation; keep insurer and assistance line handy.

Emergency Contacts

117Police
124Ambulance (availability varies)
+261 20 23 480 00US Embassy Antananarivo

Quick Checklist

  • Review CDC + State Department updates
  • Start malaria prevention plan before departure
  • Pack repellent (DEET/picaridin) and long-sleeve clothing
  • Carry backup funds and emergency contacts
  • Enroll in STEP at step.state.gov

Map

Top Things to Do

Discover attractions, tours and experiences.

Best Restaurants

Find top-rated places to eat.